其它名称:免疫球蛋白IgG4蛋白,IgG4蛋白,IgG4 protein
货号:G7043
种类:抗原
应用:Standard
特异性:Human IgG4
来源:重组蛋白
存贮:-20℃
产品说明
IgG1 immunoglobulin is most prevalent (>50%) and the IgG4 variety constitutes less than 5%. IgG4 has disulfide bonds linking the heavy chains unsteadily, allowing their separation and forming 2 antigen-binding sites, so that the bispecific antibody is asymmetric with an unclear in vivo role. IgG4 interacts with the Fc portion of IgG1–3 and not through the Fab-Fc, as occurs with other immunoglobulins, and has rheumatoid factor activity. Therefore, IgG4 has little or no cross-reactivity between antigens and rarely forms immune complexes having no complement activation capacity
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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