α1微球蛋白（α1-MG）抗原

货号：G7023

简介：
α1微球蛋白，α1-Microglobulin protein,human
α1-Microglobulin is one of the three original members of the lipocalin superfamily. It has been found in mammals, birds, amphibians and fish and is distributed in plasma and extravascular compartments of all organs. α1-Microglobulin has a free cysteine side-chain located in a flexible loop, giving the protein reductase and dehydrogenase properties with a broad biological substrate specificity. Three lysyl residues located around the opening of the lipocalin pocket carry yellow-brown modifications originating from the binding and degradation of heme and kynurenin, the latter a tryptophan metabolite. We have suggested that α1-microglobulin is involved in defending tissues against oxidation by heme, kynurenin and reactive oxygen species.