环瓜氨酸肽（CCP-BSA）抗原

其它名称：CCP-BSA,CCP抗原

货号：C7021a

种类：抗原

应用：POCT，LETIA

特异性：Human CCP

来源：Synthetic

存贮：-20℃

产品说明

More than 90% Rheumatoid arthritis patients have autoantibodies which recognise proteins in which arginine residues have been modified to citrulline.  This process may well be the cause of the inflammatory process since citrullinated proteins and the enzymes responsible for producing them are found in inmflamed synovium.  These antibodies are detected in the laboratory using artificial cyclic citrulline peptides (anti-CCP Ab). This assay is far more sensitive and specific than rheumatoid factor for the diagnosis of rheumatoid arthritis and some childhood arthritides.  However the 2009 NICE guidelines (bizarrely) recommend the continued use of rheumatoid factor based on cost effectiveness.