cTnI antibody

Troponin (Tn) is a major regulator of muscle tissue contraction and is composed of three subtypes: troponin C (TnC), troponin T (TnT), and troponin I (TnI). Troponin I is divided into three subtypes: fast skeletal muscle subtype (fTnI), slow skeletal muscle subtype (sTnI) and myocardial subtype (cTnI). cTnI has a molecular weight of 24KDa, and cTn exists in cardiomyocytes in the form of CTNi-C-T complex and free cTnI.

The molecular weight of TnC is 18KDa, which binds to calcium ions. Since the structure of TnC is the same in myocardium and skeletal muscle, cTnI and cTnT are used as markers of myocardial injury.

The content of cTnI in the blood of normal people is very low. When the myocardial cells are damaged, cTnI increases rapidly in the blood. As one of the most specific and sensitive markers of myocardial infarction, it is widely used in the diagnosis and prognosis of acute coronary syndrome and myocardial infarction due to its advantages of wide diagnostic window, strong sensitivity, good specificity and reliable results.

The cTnI antibody provided by Abgree can be well used in CLIA, POCT and LETIA