TPO多抗
货号:grTP1-01A
简介:
Thyroid peroxidase is an ∼105 kDa heme-containing glycoprotein that belongs to a family of mammalian peroxidases that includes myeloperoxidase, lactoperoxidase, eosinophil peroxidase, and salivary peroxidase. TPO is located on the apical membrane of thyrocytes where it catalyzes iodination of TG and coupling of iodotyrosines to form iodothyronines attached to TG. However, in vitro studies have shown that such functions are not unique to TPO in that lactoperoxidase and myeloperoxidase can also serve as catalysts for both iodination and coupling.